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Biography
Dr Ata Akın received his
Ph.D. on Biomedical Engineering from Drexel University in 1998. While a
Research Assistant Professor at the School of Biomedical Engineering in
Drexel University during 1999 through 2001, he conducted research on the
fields of biomedical optics and biomedical information technology. In the
field of biomedical optics, he designs and develops medical instruments
to detect breast cancer and monitor the brain activity by using
functional near infrared spectroscopy. In the field of biomedical
information technology, he develops algorithms and techniques in
extracting and classifying the signals and images obtained from the body
specifically functional optical imaging data and electrogastrogram.
Research Areas
Biomedical optics, functional
near infrared spectroscopy, neuroimaging, fMRI
Tissue perfusion monitoring by optical methods
Mathematical modeling of physiological activities (neurovascular
coupling, cerebral hemodynamics, muscle metabolism)
Biomedical signal processing and medical instrumentation
Active Research Projects
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2005-2007
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Development
of an fNIRS System in Measuring the Oxidative Metabolism, DPT,
Principal Investigator
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2004-2006
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Integrated
Neuroscience Methods to Investigate Muscle Metabolism, BURF 04S101,
Principal Investigator
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2004-2005
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MR-Compatible
fNIRS System, BURF 04X102D, Principal Investigator
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2002
- 2005:
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Establishment
of a Cellular and Molecular Imaging Laboratory, supported by Bogaziçi
University Research Fund, BURF, Co-Principal investigator
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Past
Projects
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2003-2004
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Investigation
and Modeling perfusion in live tissue in vitro by optical
methods, DPT 03K120240, Principal Investigator
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2002
- 2004:
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Functional
optical imaging, supported by Drexel University, Principal investigator
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2002
- 2004:
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Quantifying
sleep disorders in patients with ADHD by simultaneous monitoring of EEG
and fNIR, supported by Bogaziçi University Research Fund, BURF 02S102,
Principal investigator
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2001
- 2002:
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Functional
optical brain imaging sensor for pilot awareness, Office of Naval
Research, Co-PI,
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2000
- 2002:
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Functional
Near Infrared Imager, Office of Naval Research, Co-PI,
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2001
- 2003:
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Impedance
Cardiography Signal Analysis, Wantagh Inc., Co-PI,
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2001
- 2002:
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A
new integrated measure of brain hemodynamics with EEG, Drexel
University, Co-PI,
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2001
- 2002:
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IAutoflourescence
markers for cancer, Drexel University, Co-PI,
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2000
- 2001:
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Real
time handheld Near Infrared Breast Cancer Imager, NIH (SBIR), PI
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Recent Publications
Articles in SCI Journals
1.
Omer Sayli , Ertugrul Burtecin
Aksel , Ata Akin, “Crosstalk and Error Analysis of Fat Layer on
Continuous Wave Near-Infrared Spectroscopy Measurements”, J Biomed Optics, Nov/Dec 2008
2.
Koray
Çiftçi, Bülent Sankur, Yasemin Kahya, Ata Akın, "Constraining the general linear model for
sensible hemodynamic response function waveforms", Med. & Biol. Engr. & Compt.,
46:779–787, 2008
3. Koray
Çiftçi, Bülent Sankur, Yasemin Kahya, Ata Akın, “Multilevel
Statistical Inference from Functional Near Infrared Spectroscopy Data
during Stroop Interference” IEEE Trans Biomed (55), 9, 2212-2220, 2008
4. U E Emir, C Oztürk, A Akın, "Multimodal
investigation of fMRI and fNIRS derived breath hold BOLD signals with an
expanded balloon model", PHYSIOL.
MEAS. 29 (1), 49-63, (2008)
5. Tunahan Çakır, Selma Alsan,
Hale Saybaşılı, Ata
Akın, Kutlu Ö Ülgen, "Reconstruction and flux analysis of
coupling between metabolic pathways of astrocytes and neurons:
application to cerebral hypoxia" Theoretical
Biology and Medical Modelling, 4:48, 2007
- Mustafa Dinler, Erdem
Kaşıkçıoğlu, Ata Akın, Ömer Şayli,
Cihan Aksoy, Ahmet Öncel, Ender Berker, “Exercise capacity and
oxygen recovery half times of skeletal muscle in patients with
fibromyalgia,” Rheumatol. Int.
27, 311-313, 2007
- Ceyhun B. Akgül, Ata Akın, Bülent
Sankur, “Extraction of cognitive activity-related waveforms from
functioncal near-infrared signals,” Med. & Biol. Compt. & Engr 2006, 44, 945-958
- Ata Akin, Didem Bilensoy,
“Cerebrovascular reactivity to hypercapnia in migraine patients
measured with near-infrared spectroscopy” Brain Research, (1107), 206-214, 2006
- Ata Akın, Didem Bilensoy, Uzay E.
Emir, Murat Gülsoy, Selçuk Candansayar and Hayrunnisa Bolay, “Cerebrovascular dynamics in
patients with migraine: Near-infrared spectroscopy study” Neuroscience Letters, (400),
86-91, 2006
- Erdem Kasikcioglu, Armagan Arslan,
Berrin Topcu, Omer Sayli, Hulya Akhan, Huseyin Oflaz, Ata Akın,
Abidin Kayserilioglu, Mehmet Meric, “Cardiac fatigue and oxygen
kinetics after prolonged exercise” International Journal of Cardiology (108), 286-288, 2006
- Sinem Tiveci, A.Akın, T.
Çakır, H. Saybaşılı, K. Ülgen, “Modeling of Calcium
dynamics in brain energy metabolism and Alzheimer’s disease,” Computational Biology and
Chemistry, 29 (2), 151-162, 2005
- Ceyhun Burak Akgül, Bülent Sankur, Ata
Akın, “Spectral Analysis
of Event-Related Hemodynamic Responses in Functional Near Infrared
Spectroscopy”, Journal of Computational
Neuroscience (18)
67-83, 2005.
- A.Akın and H. H. Sun “Non-invasive
measurement of gastric motility with fast Electrogastrogram (fEGG)” Physiological Measurement, 23, 505–519, 2002
14.
A.Akın, H.
H. Sun, “Time and Frequency Methods for Detecting Spike Activity of
Stomach,” Med. & Biol. Engr.
& Compt., vol. 37, pp. 381-390, 1999
Selected Conference Proceeedings
- Uzay E Emir, C. Öztürk, Ata Akın,
Investigating fMRI and
fNIRS signal with balloon model during breath hold task,
ISMRM-ESMRMB Joint Annual Meeting in Berlin, Germany.
2007
- Mustafa Fidan, Ata Akın, "Effect
of tissue heterogeneity on detectability of optical signals"
Proc. of SPIE Vol. 6084 60840M-1-10, 2006
- Devrim Erdem, Ömer Şayli, Mustafa
Karahan, A. Akın, "Measurement of quadriceps endurance by
fNIRS" Proc. of SPIE Vol. 6081 608102-1-7, 2006
- E.Burteçin Aksel, Ata Akın "The effect of Anisotropy constant on
Distribution of weight of diffuse-reflected photon packets on a
hypothetical hemisphere-shaped detector" Proc. of SPIE Vol.
6084 608403-1-7, 2006
- Ömer Şayli, Ata Akın, "Two-distance partial pathlength
method for accurate measurement of muscle oxidative metabolism using
fNIRS" Proc. of SPIE Vol. 6084 60840O-1-8, 2006
- Akın Yücetaş, Ömer
Şayli, Mustafa Karahan, Ata
Akın, "Measurement of Oxidative Metabolism of the
Working Human Muscles by Near Infrared Spectroscopy," Proc. of
SPIE Vol. 6081 608103-1-7, 2006
- K. Çiftçi, Yasemin
Kahya, Bülent Sankur, Ata
Akın, “Complexity Analysis Of
Functional Near-Infrared Spectroscopy Signals,” EUSIPCO 2005,
Antalya
- E. B. Aksel,
A.Akın,
“Distribution of exit angles of diffuse reflected photons,” Proc.
SPIE, Photonics West 2005, San Jose, CA, ABD
- U. Emir, A. Ademoglu, C. Öztürk, K.
Aydin, T. Demiralp, A. Kurt, A. Dincer, A. Akın, Design of an MR compatible fNIRS System“ Proc. SPIE, Photonics West 2005,
- Ata Akın, Uzay E. Emir, Serhan Kalsın, Ömer
Şayli, “Frequency components in breathholding experiments,”
Proc. SPIE, Photonics West 2005,
- A.Akın, S. Bunce, “Behavioral reaction times are
correlated with frequency shifts in optical imaging signals,” Proc.
SPIE, Photonics West 2005,
- Ata Akın, Uzay E. Emir, Didem Bilensoy, Gulin
Erdogan,Selcuk Candansyar, Hayrunnisa Bolay, “fNIRS measurements in
migraine, “Proc. SPIE, Photonics West 2005,
- Ata Akın, U. E. Emir, H. Bolay, “Cerebral
hemodynamic reactivity measured by near infrared spectroscopy in
migraineurs” Proc.IEEE 2005 IEEE EMBS 27th Annual Conference
Shanghai, China, September 1-4, 2005,
- Emir E. U., Şayli Ö., Aydın
K., Demiralp T., Ademoğlu A., Öztürk C., Akın A., “Effect of repetitive breathholding on
BOLD and fNIRS signals,” BMES 2004 Fall Meeting, 14-16 Ekim 2004,
Philadelphia, USA, 2004
- Şayli, Ö. Emir E. U., Akın A. “Oxidative
metabolism differences in muscles measured by near infrared
spectroscopy,” BMES 2004 Fall Meeting, 14-16 Ekim 2004,
Philadelphia, USA, 2004
- Tiveci S, Çakır T,
Saybaşılı H, Akın
A, Ülgen K, “Calcium dynamics in Brain-Energy Metabolism and
Alzheimer’s Disease ” FEBS 2004
Courses
BM
402 Engineering in Medicine [Link]
Undergraduate course, covers fundamentals of biomedical engineering
principles. Introduce the common biomedical instruments and techniques and
their principles to motivate the students in generating creative ideas
for novel and better medical systems
BM
519 Biosensors
[Link]
Graduate course, Basics of biosensor technology and applications,
Introduce the concepts of sensing in biology, engineering principles,
fabrication and instrumentation of biosensors, medical applications of
biosensors
BM
554 Modeling of Biological Systems [Link]
Graduate course,
Tools
of modeling, Laplace Transform, parametric, non-parametric estimation
techniques, physiological control systems, pharmacokinetic,
pharmacodynamic models, compartment models, cellular dynamics, complex
dynamics in biology
BM 580 Computational Cell
Biology
Laboratory
Biomedical Optical Imaging and
Sensors Laboratory
Biophotonics Laboratory
Cellular and Molecular Imaging Lab
Medical Imaging Lab
Biomedical Information
Technology Lab (Drexel University)
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